Through the 2D interface you can interact with Pikachu, Snorlax, Charmander, and lots of other Pokémon from every edition. The controls couldn't be simpler – just tap the different characters and objects to do actions. For example, when it's lunchtime you simply have to go upstairs and associate each food with the Pokémon that asks for it.
With Pokémon Playhouse you can also get Pokémon eggs that, upon hatching, give you new species. Like this you've got to divide your attention to care for all of them without missing any details.
Pokémon Playhouse is quite a fun game with which little ones can have a great time caring for and playing with lots of different Pokémon. Just put yourself in the shoes of this caretaker and start meeting the needs of every creature.